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PIK3CA-activating mutations and chemotherapy sensitivity in stage II–III breast cancer

✍ Scribed by Cornelia Liedtke, Luca Cardone, Attila Tordai, Kai Yan…

Book ID
120699267
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
143 KB
Volume
10
Category
Article
ISSN
1465-5411

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## Abstract Exome sequencing of human breast cancers has revealed a substantial number of candidate cancer genes with recurring but infrequent somatic mutations. To determine more accurately their mutation prevalence, we performed a mutation analysis of 36 novel candidate cancer genes in 96 human b