𝔖 Bobbio Scriptorium
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Physiologically-Based Pharmacokinetic Modeling

✍ Scribed by Andersen, Melvin E.


Book ID
119975485
Publisher
Drug Information Association
Year
1994
Tongue
English
Weight
528 KB
Volume
28
Category
Article
ISSN
0092-8615

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Physiologically based pharmacokinetic mo
✍ Kannan Krishnan; Lee C.B. Crouse; Matthew A. Bazar; Michael A. Major; Gunda Redd πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 369 KB

## Abstract A physiologically based pharmacokinetic (PBPK) model for simulating the kinetics of cyclotrimethylene trinitramine (RDX) in male rats was developed. The model consisted of five compartments interconnected by systemic circulation. The tissue uptake of RDX was described as a perfusion‐lim