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Physiological functions of D-amino acid oxidases: from yeast to humans

✍ Scribed by L. Pollegioni; L. Piubelli; S. Sacchi; M. S. Pilone; G. Molla

Publisher
Springer
Year
2007
Tongue
English
Weight
885 KB
Volume
64
Category
Article
ISSN
1420-682X

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## Abstract In the brain, the human flavoprotein D‐amino acid oxidase (hDAAO) is involved in the degradation of the gliotransmitter D‐serine, an important modulator of NMDA‐receptor‐mediated neurotransmission; an increase in hDAAO activity (that yields a decrease in D‐serine concentration) was rece