Apparent partition coefficients Papp, of beta-lactam antibiotics were determined in octanol-water and 2-methylpropanol-water systems at various pH values. The pKa values also were determined by potentiometry under the conditions of partition experiments. The intrinsic partition coefficients for the
Physicochemical Properties of Quinolone Antibiotics in Various Environments
โ Scribed by Hyoung-Ryun Park; Tae Heung Kim; Ki-Min Bark
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 24 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
๐ SIMILAR VOLUMES
The reaction of 7-ehloro-l-eyelopropyl-6-fluoro-4-oxo-l,2-dihydroquinoline-3earboxylie acid with piperazine in water was studied. The product eiprofloxacin was isolated and the impurity formed in the reaction was isolated and characterized as 1-cyelopropyl-7-chloro-6piperazinyl-4-oxo-l,2-dihydroquin
Post-column addition of a metal salt and an auxiliary chelating ligand via a sheath flow offers an alternative strategy for promoting electrospray ionization of analytes via metal cationization. In the present study, a high-performance liquid chromatography (HPLC) mass spectrometer interface that in