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Physical mapping in the region of the Bruton's tyrosine kinase and α-galactosidase A gene loci in proximal Xq22

✍ Scribed by Angela K. Sweatman; Linda A. D. Bradley; Ruth C. Lovering; Marie-Anne J. O'Reilly; Roland J. Levinsky; Christine Kinnon

Publisher: Springer
Year: 1994
Tongue: English
Weight: 427 KB
Volume: 94
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00206955

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✦ Synopsis

We have produced physical maps of the proximal part of Xq22, containing the Bruton's tyrosine kinase (BTK) and alpha-galactosidase A (GLA) gene loci, using long range physical mapping techniques and yeast artificial chromosomes (YACs). These maps reveal five previously unidentified CpG islands which could indicate the presence of other genes in this region.

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