Photodynamic Therapy: New Research

✍ Scribed by Mohamed Lotfy Taha Elsaie

• Publisher: Nova Science
• Year: 2013
• Tongue: English
• Leaves: 287
• Series: Medical Procedures, Testing and Technology
• Category: Library

✦ Synopsis

Photodynamic therapy (PDT) is currently clinically employed to treat several malignant and nonmalignant diseases. With approvals for various applications by health agencies in Europe, the US, Canada, and Japan, PDT represents the method of choice for treatment of age-related macular degeneration and is appreciated as a minimally invasive therapeutic procedure to treat skin, esophageal, head and neck, lung, and bladder cancers with high cure rates, nearly no side effects, and excellent cosmetic outcomes. Current basic research and clinical studies will help to further integrate PDT as a mainstream procedure for cancer treatment. This book presents an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.

✦ Table of Contents

Introduction

1. Contrasting Facets of Nanoparticles-Based Phototherapy: Photo-Damage and Photo-Regeneration
   (Julie Garrier, Vadzim Reshetov, Vladimir Zorin, François Guillemin, and Lina Bezdetnaya

2. Nanostructured Third Generation Photosensitizers for Anticancer Photodynamic Therapy
   (Luis Alexandre Muehlmann, João Paulo Figueiró Longo and Ricardo Bentes de Azevedo)

3. The Role Of Phagocytosis In Cell Deaths By Photodynamic Therapy
   (E. Panzarini, V. Inguscio and L. Dini)

4. Photodynamic Treatment of Actinic Keratosis using Ameluz®: Recapitulation of Clinical Phase III Studies in the Light of Novel Preclinical Research
   (Ben Novak, Roxane Schulten, Thomas Dirschka, Rolf-Markus Szeimies, Montserrat Foguet and Hermann Lübbert)

5. Cellular Aspects of Photodynamic Therapy with Hypericin
   (Jaromír Mikeš, Rastislav Jendželovský and Peter Fedoročko)

6. Effect of Liposomal Photosensitizer as Advanced Photodynamic Therapy
   (Yasuyuki Sadzuka)

7. Antimicrobial Photodynamic Therapy in Periodontics and Implantology
   (Arthur Belem Novaes Jr. and Umberto Demoner Ramos)

8. Cell Death and Resistance Mechanisms Triggered by Photodynamic Therapy
   (Viviana A. Rivarola, Natalia B. Rumie Vittar, María Julia Lamberti, Laura Milla Sanabria, María Florencia Pansa, Ivana M. Fernández, Ingrid S. Cogno and Matías E. Rodríguez)

9. Photodynamic Therapy in Dermatology: What’s New?
   (Abeer Tawfik, NILES, Giza, Egypt and Mohamed L. Elsaie)

10. Dendrimer-based Drug Delivery System for Efficient Delivery of Hydrophilic Photosensitizer in Photodynamic Therapy of Cancer
    (Karthikeyan Krishnamoorthy, Anish Babu, Murugesan Ramachandran and
    Jeyasubramanian Kadarkaraithangam)

Index