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Photodynamic therapy-induced apoptosis is mediated by activation of CD-95 (FAS/APO-1)

✍ Scribed by Ahmad, Nihal; Gupta, Sanjay; Mukhtar, Hasan


Book ID
123242464
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
177 KB
Volume
16
Category
Article
ISSN
0923-1811

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Mechanisms of CD95 (APO-1/Fas)-mediated
✍ Marcus E Peter; Peter H Krammer πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 English βš– 725 KB

This review covers recent advances of CD95 signaling. It focuses on CD95-interacting molecules, formation of the death inducing signaling complex and the role of caspases, particularly caspase-8, and their death substrates. We also discuss the relevance of mitochondria in the CDg5-mediated apoptotic