𝔖 Bobbio Scriptorium
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Photoaffinity Labeling Introduction

✍ Scribed by Matthew S. Plate


Book ID
111412251
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
196 KB
Volume
65
Category
Article
ISSN
0031-8655

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A photolabel, a biotin tag, and a moenomycin ligand have been attached orthogonally to the three functional groups of isoserine to provide compound 13 that is to be used in anity labeling of penicillin binding protein 1b. The urethane group in 13 can be cleaved with n-butylamine in methanol or water