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Phosphorylation of Tyrosine in the Carboxyl-Terminal Tryptic Peptide of pp60c-src

✍ Scribed by Andrew P. Laudano and John M. Buchanan


Book ID
123632510
Publisher
National Academy of Sciences
Year
1986
Tongue
English
Weight
974 KB
Volume
83
Category
Article
ISSN
0027-8424

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Structural basis for the activity of pp6
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Conformational searches on three closely related pp60 c-src protein tyrosine kinase inhibitors of varying potencies were performed to determine a structural basis for their activity. The first was a linear peptide (PDNEYAFFQf), the second its 10-membered cyclic analogue, and the third a cyclic analo