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Cyclic Peptides as Probes of the Substrate Binding Site of the Cytosolic Tyrosine Kinase, pp60c-src

✍ Scribed by John S. McMurray; Raymond J.A. Budde; She Ke; Nihal U. Obeyesekere; Wei Wang; Latha Ramdas; Claire A. Lewis


Book ID
115567164
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
104 KB
Volume
355
Category
Article
ISSN
0003-9861

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We have recently determined that -Ile-Tyr- were the two critical residues as a peptide substrate for p60c-src protein tyrosine kinase (Lou, Q. et al., Lett. Peptide Sci., 1995, 2, 289). Here, we report on the design and synthesis of a secondary 'one-bead, one-compound' combinatorial peptide library