Structural basis for the activity of pp6
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Ninad V. Prabhu; Subeeh A. Siddiqui; John S. McMurray; B. Montgomery Pettitt
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Article
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2001
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Wiley (John Wiley & Sons)
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English
⚖ 444 KB
👁 2 views
Conformational searches on three closely related pp60 c-src protein tyrosine kinase inhibitors of varying potencies were performed to determine a structural basis for their activity. The first was a linear peptide (PDNEYAFFQf), the second its 10-membered cyclic analogue, and the third a cyclic analo