Conformational searches on three closely related pp60 c-src protein tyrosine kinase inhibitors of varying potencies were performed to determine a structural basis for their activity. The first was a linear peptide (PDNEYAFFQf), the second its 10-membered cyclic analogue, and the third a cyclic analo
โฆ LIBER โฆ
Host cell protein tyrosine kinases are activated during the entry of Listeria monocytogenes : Possible role of pp60c-src family protein kinases
โ Scribed by Nathalie Van Langendonck; Philippe Velge; Elisabeth Bottreau
- Book ID
- 109322247
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 318 KB
- Volume
- 162
- Category
- Article
- ISSN
- 0378-1097
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Solid-phase ELISAs for the determination of EGF receptor (EGF-R) and pp60c-src tyrosine protein kinase activity are described. The methods were developed and optimized using purified recombinant EGF-R intracellular domain (ICD) and pp60c-src tyrosine protein kinases. A standardized assay that utiliz