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Phosphorylation by Akt disables the anti-oncogenic activity of YB-1

✍ Scribed by Bader, A G; Vogt, P K

Book ID
110072709
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
178 KB
Volume
27
Category
Article
ISSN
0950-9232

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## Abstract MAX dimerization protein 1 (MAD1) is a transcription suppressor that antagonizes MYC‐mediated transcription activation, and the inhibition mechanism occurs mainly through the competition of target genes' promoter MYC binding sites by MAD1. The promoter binding proteins switch between MY