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Phosphorylated 4E-binding protein 1 (p-4E-BP1): a novel prognostic marker in human astrocytomas

✍ Scribed by Penelope Korkolopoulou; Georgia Levidou; Elias A El-Habr; Christina Piperi; Christos Adamopoulos; Vassilis Samaras; Efstathios Boviatsis; Irene Thymara; Eleni-Andriana Trigka; Stratigoula Sakellariou; Nikolaos Kavantzas; Efstratios Patsouris; Angelica A Saetta

Book ID
114729180
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
690 KB
Volume
61
Category
Article
ISSN
0309-0167

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Increased phosphorylation of the translational repressor protein 4E-BP1 was found in the cell line derived from the tumor induced in Syrian hamster by Rous sarcoma virus (RSV). This was accompanied by its dissociation from the complex with initiation factor eIF4E. The ribosomal S6 protein kinase p70