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Cell cycle-dependent phosphorylation of the translational repressor eIF-4E binding protein-1 (4E-BP1)

✍ Scribed by Kate J. Heesom; Alexandra Gampel; Harry Mellor; Richard M. Denton


Book ID
114318516
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
350 KB
Volume
11
Category
Article
ISSN
0960-9822

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## Abstract To clarify the higher eukaryotic initiation factor 4E (eIF4E) binding selectivity of 4E‐binding protein 2 (4E‐BP2) than of 4E‐BP1, as determined by Trp fluorescence analysis, the crystal structure of the eIF4E binding region of 4E‐BP2 in complex with m^7^GTP‐bound human eIF4E has been d