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Activation of p53 stimulates proteasome-dependent truncation of eIF4E-binding protein 1 (4E-BP1)

✍ Scribed by Constantina Constantinou; Androulla Elia; Michael J. Clemens

Book ID
119739580
Publisher
Portland Press
Year
2008
Tongue
English
Weight
434 KB
Volume
100
Category
Article
ISSN
0248-4900

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Structural scaffold for eIF4E binding selectivity of 4E-BP isoforms: crystal structure of eIF4E binding region of 4E-BP2 and its comparison with that of 4E-BP1
✍ Ai Fukuyo; Yasuko In; Toshimasa Ishida; Koji Tomoo πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 513 KB

## Abstract To clarify the higher eukaryotic initiation factor 4E (eIF4E) binding selectivity of 4E‐binding protein 2 (4E‐BP2) than of 4E‐BP1, as determined by Trp fluorescence analysis, the crystal structure of the eIF4E binding region of 4E‐BP2 in complex with m^7^GTP‐bound human eIF4E has been d