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Biophysical Studies of eIF4E Cap-binding Protein: Recognition of mRNA 5′ Cap Structure and Synthetic Fragments of eIF4G and 4E-BP1 Proteins

✍ Scribed by Anna Niedzwiecka; Joseph Marcotrigiano; Janusz Stepinski; Marzena Jankowska-Anyszka; Aleksandra Wyslouch-Cieszynska; Michal Dadlez; Anne-Claude Gingras; Pawel Mak; Edward Darzynkiewicz; Nahum Sonenberg; Stephen K. Burley; Ryszard Stolarski

Book ID
117142765
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
599 KB
Volume
319
Category
Article
ISSN
0022-2836

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✍ Ai Fukuyo; Yasuko In; Toshimasa Ishida; Koji Tomoo 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 513 KB

## Abstract To clarify the higher eukaryotic initiation factor 4E (eIF4E) binding selectivity of 4E‐binding protein 2 (4E‐BP2) than of 4E‐BP1, as determined by Trp fluorescence analysis, the crystal structure of the eIF4E binding region of 4E‐BP2 in complex with m^7^GTP‐bound human eIF4E has been d