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Phosphorus pentoxide in organic synthesis. XX. Synthesis of N-aryl-7H-pyrrolo[2,3-d]pyrimidin-4-amines

✍ Scribed by Anker Jørgensen; Khairy A. M. El-Bayouki; Erik B. Pedersen

Book ID
112127896
Publisher
Journal of Heterocyclic Chemistry
Year
1985
Tongue
English
Weight
269 KB
Volume
22
Category
Article
ISSN
0022-152X

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📜 SIMILAR VOLUMES

Phosphorus Pentoxide in Organic Synthesi
Phosphorus Pentoxide in Organic Synthesis, XII. Synthesis of 7H-Pyrrolo[2,3-d]pyrimidin-4-amines
✍ Jφrgensen, Anker ;Girgis, Nabih S. ;Pedersen, Erik B. 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 378 KB

## Abstract A one‐step synthesis for the preparation of a new series of substituted 7__H__‐pyrrolo[2,3‐__d__]pyrimidin‐4‐amines **2** is described. The method consists in heating the corresponding pyrrolo [2,3‐__d__]pyrimidin‐4(3__H__)‐ones **1** in a mixture of phosphorus pentoxide, __N__,__N__‐di

Phosphorus pentoxide in organic synthesi
Phosphorus pentoxide in organic synthesis, VII. Synthesis of 3-aryl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-imines
✍ Girgis, Nabih S. ;Jørgensen, Anker ;Pedersen, Erik B. 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 399 KB

## Abstract The title compounds **2** were prepared by treating 2‐(acetylamino)‐3‐pyrrolecarbonitriles **1** with a mixture of phosphorus pentoxide, __N,N__‐dimethylcyclohexanamine, and an appropriate arylamine hydrochloride at 150–180°C. The importance of using absolutely anhydrous arylamine hydro