One-Pot Synthesis of 5-Methyl-3H-pyrrolo[2,3- d ]pyrimidin-4(7H)-one
โ Scribed by Kanamarlapudi, Ramanaiah C.; Bednarz, Mark; Wu, Wenxue; Keyes, Philip
- Book ID
- 118021525
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 152 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1083-6160
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract magnified image A relatively short and efficient method for the utilization of 4,6โdichloroโ2โmethylthioโ5โnitropyrimidine (**1**) in the synthesis of the poly substituted pyrrolo[3,2โ__d__]pyrimidinโ7โone 5โoxides (**6a**โg) is reported. Some new 4โsubstituted 6โchloroโ2โmethylthioโ5โ
1,3-Dihydro-2H-indol-2-ones (oxindoles) and 1,3-dihydro-2H-pyrrolopyridin-2-ones (azaoxindoles) are useful scaffolds that have been explored for various pharmaceutical uses. Herein we report the synthesis of 2-chloro-5,7-dihydro-6H-pyrrolo [2,3d]pyrimidin-6-one (5) and its derivatives, and the appli