✦ LIBER ✦

Synthesis of 2-chloro-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one

✍ Scribed by Mui Cheung; Philip A Harris; Karen E Lackey

Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 78 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)02219-x

No coin nor oath required. For personal study only.

✦ Synopsis

1,3-Dihydro-2H-indol-2-ones (oxindoles) and 1,3-dihydro-2H-pyrrolopyridin-2-ones (azaoxindoles) are useful scaffolds that have been explored for various pharmaceutical uses. Herein we report the synthesis of 2-chloro-5,7-dihydro-6H-pyrrolo [2,3d]pyrimidin-6-one (5) and its derivatives, and the application of 5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-ones (diazaoxindoles) as novel scaffold to kinase research areas.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of 2-Chlo

ChemInform Abstract: Synthesis of 2-Chloro-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one.

✍ Mui Cheung; Philip A. Harris; Karen E. Lackey 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis of 2,4-disubstituted 6-phenyl-

Synthesis of 2,4-disubstituted 6-phenyl-7H-pyrrolo[3,2-d]-pyrimidin-7-one 5-oxides

✍ Inga Cikotiene; Erika Pudziuvelyte; Algirdas Brukstus 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 256 KB

## Abstract magnified image A relatively short and efficient method for the utilization of 4,6‐dichloro‐2‐methylthio‐5‐nitropyrimidine (**1**) in the synthesis of the poly substituted pyrrolo[3,2‐__d__]pyrimidin‐7‐one 5‐oxides (**6a**‐g) is reported. Some new 4‐substituted 6‐chloro‐2‐methylthio‐5‐

ChemInform Abstract: Synthesis of 2,4-Di

ChemInform Abstract: Synthesis of 2,4-Disubstituted 6-Phenyl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-Oxides.

✍ Inga Cikotiene; Erika Pudziuvelyte; Algirdas Brukstus 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

5-(4-Chlorophenoxy)-3,6-diphenyl-2-thi

5-(4-Chlorophenoxy)-3,6-diphenyl-2-thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one 4-chlorophenol solvate

✍ Liang, Ying ;He, Hong-Wu 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 215 KB

In the title compound, C 23 H 14 ClN 3 O 2 S 2 ÁC 6 H 5 ClO, the mean plane of the thiazolopyrimidine fragment makes dihedral angles of 64.26 (11), 77.70 (10) and 49.70 (18) with the two attached phenyl rings and the 4-chlorophenoxy fragment. The crystal packing is stabilized by intermolecular O-HÁ

5,6-Dianilino-3-(4-chlorophenyl)-3,6-d

5,6-Dianilino-3-(4-chlorophenyl)-3,6-dihydro-1,2,3-triazolo[4,5-d]pyrimidin-7-one

✍ Zhao, Jun-Feng ;Hu, Yang-Gen ;Ding, Ming-Wu ;He, Hong-Wu 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 270 KB

ChemInform Abstract: Synthesis of 1-Amin

ChemInform Abstract: Synthesis of 1-Amino-6,7-dihydro-7-(hydroxymethyl)-4-nitro-pyrrolo [1,2-f]pyrimidin-3-(5H)-one from 2-Amino-6-methylpyrimidin-3-one.

✍ Jie Liu; Weidong Liu; Zhili Zhang; Zhijian Cheng; Xiaoyan Ma; Xiaowei Wang; Juny 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 23 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v