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Phosphoinositide 3-Kinase (P110α) [PI3K(P110α)] is Critical for the Maintenance of Cardiac Function and Survival in a Setting of Heart Failure

✍ Scribed by Lynette Pretorius; Lynette Pretorius; Helen Kiriazis; Ziqiu Ming; Junichi Sadoshima; Seigo Izumo; Garry L. Jennings; Xiao-Jun Du; Julie McMullen


Book ID
119255851
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
136 KB
Volume
17
Category
Article
ISSN
1443-9506

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✍ Rommel, Christian; Vanhaesebroeck, Bart; Vogt, Peter K. 📂 Article 📅 2010 🏛 Springer Berlin Heidelberg 🌐 German ⚖ 353 KB

PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impact of intervention with PI3K activity are high, and progress in the clinical arena is being monitored by many. However, targeted therapies almost inva