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[Current Topics in Microbiology and Immunology] Phosphoinositide 3-kinase in Health and Disease Volume 347 || Comparing the Roles of the p110α and p110β Isoforms of PI3K in Signaling and Cancer

✍ Scribed by Rommel, Christian; Vanhaesebroeck, Bart; Vogt, Peter K.

Book ID
124070486
Publisher
Springer Berlin Heidelberg
Year
2010
Tongue
German
Weight
353 KB
Edition
2011
Category
Article
ISBN
3642148166

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✦ Synopsis

PI3K has become a very intense area of research, with over 2000 publications on PI3K in PubMed for 2009 alone. The expectations for a therapeutic impact of intervention with PI3K activity are high, and progress in the clinical arena is being monitored by many. However, targeted therapies almost invariably encounter roadblocks, often exposing unresolved questions in the basic understanding of the target

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