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Phosphatidylinositol 3-kinase is involved in the colony-stimulating factor-1-induced spreading of macrophages and osteoclasts

✍ Scribed by Felix, R.; Hotstetter, W.; Bösiger, J.; Thelen, M.


Book ID
122110270
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
149 KB
Volume
17
Category
Article
ISSN
8756-3282

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## Abstract Mouse bone marrow‐derived macrophages proliferate in the presence of macrophage colony‐stimulating factor (M‐CSF), granulocyte‐macrophage colony‐stimulating factor, or IL‐3, but undergo apoptosis in their absence. Inhibition of extracellular signal‐regulated kinases (ERK)‐1/2 blocks gro