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Phosphatidylinositol 3-kinase/Akt pathway is involved in transforming growth factor-β1-induced phenotypic modulation of 10T1/2 cells to smooth muscle cells

✍ Scribed by Sheng-Chieh Lien; Shunichi Usami; Shu Chien; Jeng-Jiann Chiu

Book ID: 113527900
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 350 KB
Volume: 18
Category: Article
ISSN: 0898-6568
DOI: 10.1016/j.cellsig.2005.10.013

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## Abstract Transforming growth factor‐beta (TGF‐beta), a potent cytokine, modulates a wide variety of biological responses. Among its actions, TGF‐beta can augment prostaglandin synthesis in several cell types. Although TGF‐beta alone has no effect on prostaglandin production in Swiss 3T3 cells, w