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Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases

✍ Scribed by Shamshad Cockcroft

Book ID
116273397
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
507 KB
Volume
1791
Category
Article
ISSN
1388-1981

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## Abstract Type I phosphatidylinositol 4‐phosphate 5‐kinase (PI4P5K) catalyzes the phosphorylation of phosphatidylinositol 4 phosphate [PI(4)P] at carbon 5, producing phosphatidylinositol 4,5 bisphosphate [PI(4,5)P2]. Phosphatidic acid (PA) activates PI4P5K in vitro and plays a central role in the