Induction of protein kinase C down-regul
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Michel Savart; Pascale Letard; Sandrine Bultel; Andre Ducastaing
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Article
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1992
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John Wiley and Sons
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French
β 505 KB
## Abstract Using a calpain/protein kinase C (PKC) complex, we were able to reproduce, __in vitro__, the induction of PKC downβregulation by the phorbol ester 12βOβtetradecanoylβphorbolβ13βacetate (TPA) which had been previously observed in cells. We show that TPA initiates this phenomenon by promo