Phenylphosphonate monoester analogs of cocaine. Potential haptens for the generation of catalytic antibodies
β Scribed by Nizal S. Chandrakumar; Christopher P. Carron; Debra M. Meyer; Patrick M. Beardsley; Susan A. Nash; Linda L. Tam; Michael Rafferty
- Book ID
- 108477038
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 278 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0960-894X
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π SIMILAR VOLUMES
The conditions under which the reduction of a-hydroxy azides by triphenylphosphine to aziridines is diverted to produce the corresponding aminoalcohol have been established.
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In order to assess a novel strategy for catalytic activation of a new prodrug of doxorubicin, a new hapten has been designed and prepared, which can be used to induce an immune response from which catalytic antibodies (cAbs) may be produced.