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Phenotypic analysis of the medullary-type CD4−CD8+thymocytes in mice

✍ Scribed by Tian Tian; Hongfang Wang; Meifu Feng; Weifeng Chen

Publisher
Springer
Year
2000
Tongue
English
Weight
394 KB
Volume
45
Category
Article
ISSN
1001-6538

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CD4+CD8+ thymocytes develop into CD4 or
CD4+CD8+ thymocytes develop into CD4 or CD8 single-positive cells in athymic nude mice*
✍ Hidekazu Tamauchi; Norikazu Tamaoki; Sonoko Habu 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 355 KB

A differentiation pathway from CD4+CD8+ cells to CD4+CD8- or CD4-CD8+ cells was investigated in athymic nude mice. Using fluorescence-activated cell sorter, CD4+CD8+ cells were sorted out from AKR thymocytes (H-2k, Thy-1.1) stained with two monoclonal antibodies against CD4 and CD8 (anti-L3T4 and an