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A cd3− subset of cd4−8+ thymocytes: a rapidly cycling intermediate in the generation of cd4+8+ cells

✍ Scribed by H. Robson MacDonald; Ralph C. Budd; Rawleigh C. Howe

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
670 KB
Volume
18
Category
Article
ISSN
0014-2980

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Ontogeny of T cell maturation in LEC mut
Ontogeny of T cell maturation in LEC mutant rats which bear a congenital arrest of maturation from CD4+CD8+ to CD4+CD8− thymocytes
✍ Takashi Agui; Tohru Sakai; Kozo Matsumoto 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 421 KB 👁 1 views

## Abstract LEC rats bear a congenital deficiency in CD4^+^CD8^−^ thymocytes and peripheral CD4^+^ T cells, and consequently a deficiency in T~h~ cell functions. Ontogeny of T cell maturation in normal and LEC mutant rats was, therefore, investigated. Prenatal development of thymocytes in normal ra