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Phenacylthioimidazolines and 3-aryl-5,6-dihydroimidazo[2,1-b]thiazoles with antidepressant activity

โœ Scribed by Sharpe, C. J.; Shadbolt, R. S.; Ashford, A.; Ross, J. W.


Book ID
118163725
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
636 KB
Volume
14
Category
Article
ISSN
0022-2623

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A facile approach to the synthesis of 2,3,6-trisubstituted-5,6-dihydroimidazo[2,1-b]thiazole was reported. A resin bound cyclic thiourea was formed by the treatment of a resin bound diamine with 1,1'-thiocarbonyldiimidazole, and then reacted with a ฮฑ-haloketone to generate a resin bound isothiourea.