๐”– Bobbio Scriptorium
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Phase separation of excipients during lyophilization: Effects on protein stability

โœ Scribed by Theodore W. Randolph

Book ID
109388843
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
186 KB
Volume
86
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES

Effect of excipients on the stability an
Effect of excipients on the stability and structure of lyophilized recombinant human growth hormone
โœ Henry R. Costantino; Karen G. Carrasquillo; Rocio A. Cordero; Marco Mumenthaler; ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 161 KB

We have investigated the effect of mannitol, sorbitol, methyl R-D-mannopyranoside, lactose, trehalose, and cellobiose on the stability and structure of the pharmaceutical protein recombinant human growth hormone (rhGH) in the lyophilized state. All excipients afforded significant protection of the p