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Phase I/II trial of weekly docetaxel and concomitant radiotherapy for squamous cell carcinoma of the head and neck

✍ Scribed by Masato Fujii; Mamoru Tsukuda; Bunsuke Satake; Akira Kubota; Akinori Kida; Naoyuki Kohno; Kenji Okami; Yukio Inuyama


Publisher
Springer
Year
2004
Tongue
English
Weight
428 KB
Volume
9
Category
Article
ISSN
1341-9625

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## Abstract ## BACKGROUND The current Phase I/II study assessed induction docetaxel/carboplatin given weekly for 4 weeks, followed by weekly docetaxel/carboplatin and concomitant boost radiotherapy (CB‐XRT) for locally advanced head and neck squamous cell carcinoma. ## METHODS Twenty patients wi

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## Abstract ## Purpose The combination of chemotherapy and irradiation is considered the standard of care for the treatment of advanced squamous cell carcinoma of head and neck (SCCHN). Paclitaxel has shown a single‐agent activity in SCCHN. Besides, this drug is a promising radiosensitizer for som