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Radiotherapy for basaloid squamous cell carcinoma of the head and neck

✍ Scribed by Dr. James M. Larner; Dr. Ronald H. Malcolm; Dr. Stacey E. Mills; Dr. Henry F. Frierson Jr.; Dr. Evelyn R. Banks; Dr. Paul A. Levine

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
451 KB
Volume
15
Category
Article
ISSN
1043-3074

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✦ Synopsis

Basaloid squamous cell carcinoma (BSCC) of the head and neck is a recently described high-grade variant of squamous cell carcinoma. It is a biologically virulent neoplasm with a propensity for nodal, as well as systemic, metastases. Because of the limited number of published reports, we reviewed data from patients of the University of Virginia Health Sciences Center and identified 16 cases of BSCC. The intent of this study was to determine the role of radiotherapy in the treatment of BSCC and better define the clinical features of this entity. Radiotherapy alone, or in combiriation with surgery, resulted in excellent local control rates. Distant metastases, chiefly pulmonary, occurred in more than half of the patients.

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