Phase II trial of carboplatin in patients with advanced germ-cell testicular tumors and transitional cell carcinomas of the urinary tract
β Scribed by Hideyuki Akaza; Masamichi Hagiwara; Nobuhiro Deguchi; Tsuneo Kawai; Yoshiaki Satomi; Tadashi Matsuda; Tsuneharu Miki; Toyofumi Ueda; Toshihiko Kotake; Hiroshi Tazaki; Yoshio Aso; Tadao Niijima;
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 446 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0344-5704
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## Abstract ## BACKGROUND Cisplatinβbased combinations are considered to be the standard treatment for advanced transitional cell carcinoma (TCC) of the urothelium. Many of the patients are elderly with concomitant diseases or impaired renal function. We studied the tolerance and activity of the g
This is a comparative study to evaluate response rate to mitoguazone (MGBG) and vinblastine (VLB) in 52 evaluable patients with advanced transitional cell carcinoma of the urinary tract. Of 38 patients with measurable disease, two of 18 (11%) on MGBG had partial remission (95% confidence interval: 0