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Phase-II study of treatment of refractory acute leukemia with intermediate-dose cytosine arabinoside and amsacrine

โœ Scribed by U. Jehn; V. Heinemann

Publisher
Springer
Year
1993
Tongue
English
Weight
261 KB
Volume
66
Category
Article
ISSN
0939-5555

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Treatment of acute nonlymphocytic leukem
Treatment of acute nonlymphocytic leukemia in the elderly with intermediate high-dose cytosine arabinoside
โœ Letendre, Louis ;Niedringhaus, Robert D. ;Therneau, Terry M. ;Gastineau, Dennis ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 362 KB ๐Ÿ‘ 1 views

Effective treatment of the elderly patients (265 years) with acute nonlymphocytic leukemia (ANLL) remains elusive and controversial. In the present study, single-agent Cytosine Arabinoside (AM-C) was administered at an intermediate dose level (500 mg/m2 intravenously [I.V.] I-hour infusion q12 hours

Mitoxantrone and high-dose cytosine arab
Mitoxantrone and high-dose cytosine arabinoside for the treatment of refractory acute lymphocytic leukemia
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Twenty-five adult patients with refractory acute lymphocytic leukemia received salvage therapy with mitoxantrone 5 mg/m2 intravenously over 1 hour daily for 5 days and cytosine arabinoside 3 g/m2 intravenously over 2 hours every 12 hours for six doses. Overall, nine patients (36%) achieved complete