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Phase II study of dose-dense sequential doxorubicin and docetaxel for patients with advanced operable and inoperable breast cancer

✍ Scribed by Brenda W. Cooper; Tomas Radivoyevitch; Beth A. Overmoyer; Robert R. Shenk; Huong T. Pham; Judith R. Samuels; Margaret P. Parry; Paula Silverman

Publisher
Springer US
Year
2005
Tongue
English
Weight
208 KB
Volume
97
Category
Article
ISSN
0167-6806

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## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and docetaxel have single‐agent activity in several malignancies. The authors conducted a Phase I trial to evaluate the maximum tolerated dose (MTD), toxicities, and effect of dose sequencing of this combination in patients with ad