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Dose-finding phase I study of simultaneous weekly infusion with doxorubicin and docetaxel in patients with advanced breast cancer

✍ Scribed by Y. Ito; K. Aiba; N. Horikoshi; T. Saotome; T. Irie; K. Sugiyama; M. Nakane; D. Hashimoto; N. Yoshida; N. Mizunuma; S. Takahashi; Y. Tanigawara


Publisher
Springer
Year
2001
Tongue
English
Weight
87 KB
Volume
6
Category
Article
ISSN
1341-9625

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## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and docetaxel have single‐agent activity in several malignancies. The authors conducted a Phase I trial to evaluate the maximum tolerated dose (MTD), toxicities, and effect of dose sequencing of this combination in patients with ad