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Phase II study of oral etoposide for patients with advanced breast cancer

✍ Scribed by Daniel M. Atienza; Charles L. Vogel; Bruce Trock; Sandra M. Swain


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
562 KB
Volume
76
Category
Article
ISSN
0008-543X

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Idarubicin (4-demethoxydaunorubicin: DMDNR) is an orally active analogue of daunorubicin that has shown promising activity in animal and early clinical studies. We gave idarubicin in a phase II study to patients with advanced breast cancer unresponsive to hormonal manipulation and in some cases to s

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## Background: Based on the promising results of eap (etoposide, doxorubicin, and cisplatin) combination, a phase ii study of modified eap combination was performed in patients with advanced gastric cancer to evaluate the response, toxicity, and survival. ## Method: Fifty-two consecutive patients