Bleomycin given intravenously (i.v.) or intramuscularly (i.m.) in twice-weekly doses of 10 mg/mz was evaluated for efficacy and toxicity in 382 patients. Responses were observed in 11/27 Hodgkin's diseases, 10/30 lymphomas, 9/22 squamous cell cancers of ectodermal origin, 12/26 germinal cancers, and
Phase II evaluation of galactitol in head and neck cancer: A southwest oncology group study
✍ Scribed by Haas, Charles D. ;Lehane, Daniel ;Bottomley, Richard
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 208 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0098-1532
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A phase II evaluation of DAG in head and neck cancer patients produced one partial response and one patient with prolonged stable disease from nine fully evaluable patients with squamous carcinomas. One partial response was produced in a patient with anaplastic thyroid carcinoma. No drug deaths or life‐threatening toxicity were reported. Further evaluation of DAG in thyroid tumors is warranted.
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