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Phase II and pharmacokinetic study of thalidomide in Japanese patients with relapsed/refractory multiple myeloma

โœ Scribed by Hirokazu Murakami; Kazuyuki Shimizu; Morio Sawamura; Kenshi Suzuki; Isamu Sugiura; Hiroshi Kosugi; Chihiro Shimazaki; Masafumi Taniwaki; Masahiro Abe; Toshiyuki Takagi


Book ID
107618765
Publisher
Carden Jennings Publishing
Year
2009
Tongue
English
Weight
207 KB
Volume
89
Category
Article
ISSN
0925-5710

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Phase II trial of temsirolimus in patien
โœ Sherif S. Farag; Shuhong Zhang; Buffy S. Jansak; Xiaojing Wang; Eric Kraut; Kenn ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 508 KB

In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25mg I.V. weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3-4 toxicity included fat