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A systematic review of phase-II trials of thalidomide monotherapy in patients with relapsed or refractory multiple myeloma

✍ Scribed by Axel Glasmacher; Corinna Hahn; Florian Hoffmann; Ralph Naumann; Hartmut Goldschmidt; Marie von Lilienfeld-Toal; Katjana Orlopp; Ingo Schmidt-Wolf; Marcus Gorschlüter


Book ID
108673590
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
181 KB
Volume
132
Category
Article
ISSN
0007-1048

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In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25mg I.V. weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3-4 toxicity included fat