Phase II Study of Bryostatin 1 in Patients with Relapsed Multiple Myeloma
โ Scribed by Mary L. Varterasian; Pamela A. Pemberton; Kim Hulburd; Dorothy H. Rodriguez; Anthony Murgo; Ayad M. Al-Katib
- Book ID
- 110294274
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 42 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0167-6997
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In a phase II trial, 16 patients with relapsed refractory multiple myeloma received temsirolimus 25mg I.V. weekly until progression. One partial response and 5 minor responses were observed for a total response rate of 38%. The median time to progression was 138 days. Grade 3-4 toxicity included fat
Seventy-four previously treated patients with multiple myeloma were treated with Amsacrine (m-AMSA) 120 mg/m2 every 3 weeks. A good response was observed in two patients (3%), and improvement was seen in three patients (4%). Severe toxicity was observed in 33% of patients who received three or more