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Phase I trial of sorafenib in combination with ifosfamide in patients with advanced sarcoma: a Spanish group for research on sarcomas (GEIS) study

✍ Scribed by Martín-Liberal, J.; López-Pousa, A.; Broto, J. Martín; Cubedo, R.; Gallego, O.; Brendel, E.; Tirado, O. M.; Muro, X. García


Book ID
121700766
Publisher
Springer US
Year
2013
Tongue
English
Weight
293 KB
Volume
32
Category
Article
ISSN
0167-6997

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## Abstract ## BACKGROUND Combinations of high‐dose ifosfamide (IF; 10–12 g/m^2^) plus doxorubicin (DX; 50–90 mg/m^2^) have been administered to patients with advanced soft tissue sarcoma (ASTS) in an attempt to improve therapeutic efficacy. Although these combination regimens appear to yield high