Synthesis of the anti-tumor agent CI-973
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I. Victor Ekhato; James D. Hoeschele; Che C. Huang; Bela Nanavaty; Helen T. Lee
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Article
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1993
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John Wiley and Sons
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French
β 307 KB
π 1 views
## Abstract Starting from the chiral compound 1, (R)β(+)β2βmethylβ1,4β[^14^C]butanediamine 7 was synthesized in a sequence of reactions in which ^14^Cβlabel was introduce using label potassium cyanide. Compound 7 was reacted with potassium tetraiodoplatinate and silver 1,1βcyclobutanedicarboxylate