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A phase II study of CI-973 [SP-4-3(R)]- [1, 1-cyclobutane-dicarboxylato (2-)] (2-methyl-1,4-butanediamine-N, N′) platinum in patients with refractory advanced breast cancer

✍ Scribed by R. L. Theriault, Ronald S. Walters…


Book ID
120776658
Publisher
Springer
Year
1996
Tongue
English
Weight
119 KB
Volume
38
Category
Article
ISSN
0344-5704

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✍ I. Victor Ekhato; James D. Hoeschele; Che C. Huang; Bela Nanavaty; Helen T. Lee 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 307 KB 👁 1 views

## Abstract Starting from the chiral compound 1, (R)‐(+)‐2‐methyl‐1,4‐[^14^C]butanediamine 7 was synthesized in a sequence of reactions in which ^14^C‐label was introduce using label potassium cyanide. Compound 7 was reacted with potassium tetraiodoplatinate and silver 1,1‐cyclobutanedicarboxylate