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Pharmacotherapy of intraocular pressure – part II. Carbonic anhydrase inhibitors, prostaglandin analogues and prostamides

✍ Scribed by Costagliola, Ciro; dell’Omo, Roberto; Romano, Mario R; Rinaldi, Michele; Zeppa, Lucia; Parmeggiani, Francesco


Book ID
125951180
Publisher
Informa plc
Year
2009
Tongue
English
Weight
704 KB
Volume
10
Category
Article
ISSN
1465-6566

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ChemInform Abstract: Carbonic Anhydrase
✍ C. T. SUPURAN; F. MINCIONE; A. SCOZZAFAVA; F. BRIGANTI; G. MINCIONE; M. A. ILIES 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

In order to find novel active compounds, complexes such as (I)-(III) are prepared. Whereas the parent sulfonamide shows no topical pressure-lowering effects in rabbits in a 2% solution the compounds (I) and (II) are more active than dorzolamide and thus are basis for a new generation of antiglaucoma