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Pharmacophore modeling and virtual screening studies to identify new c-Met inhibitors

✍ Scribed by Wenting Tai, Tao Lu, Haoliang Yuan, Fengxiao Wang, Haichun Liu, Shuai Lu, Ying Leng, Weiwei Zhang, Yulei Jiang, Yadong Chen

Book ID
113053397
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
845 KB
Volume
18
Category
Article
ISSN
1610-2940

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## Abstract The stem cell factor receptor (c‐Kit) has been known to play critical roles in regulating numerous aspects of cellular behavior including cell growth, differentiation, migration and metabolism. In this investigation, a three‐dimensional pharmacophore model of c‐Kit inhibitors has been e