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Pharmacology and molecular identification of gastrin releasing peptide-like receptors in human breast cancer cell lines and normal breast epithelial cells

✍ Scribed by F. Calvo; P. de Crémoux; S. Giacchetti; C. Gauvillé; F. Berthon; G. Lagier; P. Lechat

Book ID
115883769
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
119 KB
Volume
183
Category
Article
ISSN
0014-2999

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## Abstract The binding of ^125^I‐Tyr^4^ bombesin was investigated on plasma membranes of 8 human breast cancer cell lines and 2 long‐term cultures of normal human breast epithelial cells. Scatchard plots were compatible with high‐affinity, single‐site class of receptors in 3 cell lines (K~D~ of 0.