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Pharmacological Manipulation of D1-Dopamine Receptor Function in Schizophrenia

✍ Scribed by Göran C Sedvall; Per Karlsson

Book ID
114282427
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
153 KB
Volume
21
Category
Article
ISSN
1470-634X

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We studied the relationship between schizophrenia and the DdeI polymorphism in the 5 untranslated region (5UTR) of the dopamine D1 receptor (DRD1) gene. This polymorphism is an A (A1 allele) to G (A2 allele) transition in the 5 UTR of exon 2 at bp -48 (A-48G). One hundred forty-eight schizophrenics