The pharmacological activities were screened of aqueous extracts of Ocimum gratissimum in isolated rabbit jejunum (IRJ); rat stomach strip (RSS); and also its analgesic properties in mice. The extract caused a dose dependent inhibition of the rabbit jejunum spontaneous pendular movement. The blocki
Pharmacological evaluation of Hoslundia opposita extract in rodents
β Scribed by O. A. Olajide; O. O. Oladiran; S. O. Awe; J. M. Makinde
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 69 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-418X
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β¦ Synopsis
A chloroform extract of the dried root of Hoslundia opposita was studied for its analgesic, antipyretic and antiinflammatory activities. A significant protection against the acetic acid-induced writhing response in mice, and a marked lowering of the body temperature of hyperthermic mice was observed. A significant inhibition of the carrageenan-induced rat hind paw oedema was also produced. Our preliminary screening thus confirms the folklore use of Hoslundia opposita in various ailments.
π SIMILAR VOLUMES
The pharmacological activity of the dichloromethanol extract of Schinus molle L. (SM-DCM) was analysed in in vitro models. Preincubation of the isolated guinea-pig ileum or rat uterus preparations with the extract (100 mg/mL) abolished the contractile effects of histamine and serotonin respectively.